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Guajillo and Tomatillo Salsa

A vibrant Mexican-style salsa made with toasted guajillo chiles, tomatillos, and aromatics. This versatile sauce combines the sweet heat of guajillo peppers with the bright, tangy flavor of tomatillos.

4 servings
18 min
Published October 4, 2025
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Ingredients

  • •3 whole dried large guajillo or New Mexico chiles
  • •1 whole dried chile de árbol
  • •½ pound fresh tomatillos
  • •¼ cup white onion
  • •1 clove garlic
  • •1 tablespoon orange juice

Cooking Instructions

  1. 1.

    Heat a dry heavy medium skillet (not nonstick) over medium heat until hot, then toast chiles briefly on all sides, pressing flat with tongs, until slightly softened, about 3 minutes.

    3 min

  2. 2.

    Simmer tomatillos in water to cover in a small saucepan until tender, about 5 minutes. Transfer with a slotted spoon to a blender and add chiles, onion, garlic, orange juice, and 3/4 teaspoon salt. Blend until smooth (use caution when blending hot liquids). Transfer to a bowl and cool to room temperature.

    15 min

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