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Southwestern Barbecued Brisket with Ancho Chile Sauce

A flavorful barbecued brisket rubbed with a southwestern spice blend featuring ancho chile powder, cumin, and paprika, slow-cooked to perfection and served with a rich ancho chile sauce. This tender, smoky brisket is perfect for entertaining or family gatherings.

8 servings
8 hr 15 min
Published October 4, 2025

Ingredients

  • •4 teaspoons coarse kosher salt
  • •1 tablespoon golden brown sugar
  • •2 teaspoons ancho chile powder
  • •1 teaspoon paprika
  • •1 teaspoon ground cumin
  • •1 teaspoon granulated garlic
  • •1 teaspoon coarsely ground black pepper
  • •1 piece flat-cut brisket
  • •4 cups hickory or oak wood chips
  • •4 pieces disposable mini aluminum loaf pans
  • •2 pieces disposable aluminum pans
  • •1 roll Heavy-duty aluminum foil
  • •1 serving Ancho Chile Sauce

Cooking Instructions

  1. 1.

    Mix first 7 ingredients in small bowl. Rub spice blend over brisket. Wrap brisket in plastic; refrigerate at least 2 hours and up to 24 hours.

    120 min

  2. 2.

    Remove top rack from barbecue. Prepare barbecue (low heat). Light briquettes in chimney; pour onto 1 side of lower grill rack (you'll need to light more briquettes in chimney to replenish 2 or 3 more times during grilling). Drain 2 cups wood chips. Scatter 2 cups wood chips over coals. Return grill rack to barbecue. Heat barbecue to 300°F.

    30 min

  3. 3.

    Remove top rack from barbecue. Prepare barbecue (low heat). If using 2-burner grill, light 1 burner. If using 3-burner grill, do not light center burner. Drain 2 cups wood chips. Stack 2 mini loaf pans (one inside the other); fill with 1 cup wood chips. Stack remaining loaf pans; fill with 1 cup wood chips. Place pans over flame (if using 3-burner grill, place both pans on 1 lit side). Return rack to barbecue. Heat barbecue to 300°F. (If temperature rises too high on 3-burner grill, turn off burner without chips.)

    30 min

  4. 4.

    Unwrap brisket and arrange fat side up in 11 3/4 x 8 1/2 x 1 1/4-inch aluminum pan; place pan over unlit part of barbecue. Cover barbecue. Cook brisket until instant-read thermometer inserted into center registers 160°F, adjusting vents or adding more charcoal as needed (if using charcoal grill) or adjusting gas levels (if using gas grill) to maintain temperature inside barbecue grill at 250°F, about 31/2 hours. Baste brisket occasionally with pan juices and add more drained wood chips as needed.

    210 min

  5. 5.

    Remove pan with brisket. Discard pan and juices. Wrap brisket tightly in 2 wide sheets of heavy-duty foil. Place in clean 11 3/4 x 8 1/2 x 1 1/4-inch aluminum pan. Return to grill over unlit side, maintaining temperature inside grill at 250°F, until instant-read thermometer inserted into thickest part of center of brisket registers 190°F, about 1 1/2 hours longer. Transfer brisket in pan to rimmed baking sheet. Let rest at least 1 hour and up to 2 hours.

    90 min

  6. 6.

    Carefully unwrap brisket, saving any juices in foil. Transfer juices to small pitcher. Place brisket on work surface. Thinly slice brisket across grain; transfer to platter. Brush brisket with some of juices. Serve with any remaining juices and Ancho Chile Sauce.

    15 min

  7. 7.

    * Available in the spice section of many supermarkets and at Latin markets.

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