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Tortilla Casserole with Turkey

A hearty Mexican-inspired casserole layering corn tortillas with shredded turkey, fresh vegetables, cheese, and homemade tomatillo salsa. This comforting dish combines zucchini, chayote squash, corn, and green beans with layers of melted Monterrey Jack cheese and tangy sour cream.

8 servings
1 hr 50 min
Published October 4, 2025

Ingredients

  • •¾ cup corn oil
  • •18 pieces corn tortillas
  • •3 medium zucchini
  • •2 cups chayote squash
  • •1 cup corn kernels
  • •2 cups green beans
  • •2½ cups turkey
  • •2 cups Monterrey Jack cheese
  • •6 cups Salsa de Tomatillo
  • •2 cups sour cream
  • •1 tablespoon milk
  • •to taste sea salt and pepper
  • •
  • •60 pieces tomatillos
  • •8 pieces serrano chiles
  • •4 cups water
  • •5 cloves garlic
  • •1 cup cilantro
  • •2 tablespoons vegetable oil
  • •to taste sea salt
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Cooking Instructions

  1. 1.

    Prepare the Salsa de Tomatillo. In a heavy, 6-quart, nonreactive saucepan over medium-high heat, combine tomatillos, chiles, and water; bring to a boil. Reduce heat to low and simmer until the tomatillos are tender, about 10 to 12 minutes. Drain, reserving 1/2 to 1 cup of the cooking liquid. Working in batches, combine tomatillos, chiles, reserved cooking liquid, garlic, and cilantro in a blender and blend to a smooth puree. In a heavy, 12-inch, deep-sided skillet, heat the oil over medium heat and cook the tomatillo mixture for about 10 minutes, stirring often. Add salt to taste.

    25 min

  2. 2.

    Prepare the casserole. In a heavy, 10-inch skillet, heat 3/4 cup of the corn oil over medium heat until the oil shimmers. Using tongs, submerge the tortillas, one at a time, in the hot oil for about 10 seconds (the tortillas should remain pliable). Transfer to a baking sheet lined with paper towels to drain. Lightly oil a 13-by-9-inch baking dish and set aside. In a heavy, 12-inch, nonstick skillet, heat the remaining 1 tablespoon of oil over medium heat until shimmering. Add both kinds of squash and cook over medium heat about 5 minutes. Add the corn and green beans and cook until just tender, about 2 to 3 minutes. Add salt and pepper to taste.

    15 min

  3. 3.

    Preheat oven to 375 degrees. Arrange 6 of the softened tortillas in the prepared baking dish, overlapping the edges. Cover with half of the shredded turkey, half of the vegetable mixture, 1 cup of the cheese, 1 cup of the Salsa de Tomatillo, and 3/4 cup of the sour cream. Repeat the layering process with 6 additional tortillas, the remaining turkey, vegetable mixture, and cheese, 1 cup of the Salsa de Tomatillo, and 3/4 cup of the sour cream. Top with the remaining 6 tortillas. Drizzle with 1 cup of the Salsa de Tomatillo, cover with foil, and bake in preheated oven for about 50 minutes, or until heated through.

    60 min

  4. 4.

    During the last few minutes of the cooking time, heat the remaining 3 cups Salsa de Tomatillo over low heat and keep warm. In a small bowl, whisk together the remaining 1/2 cup sour cream and the milk; drizzle over the hot casserole when it comes out of the oven. Serve the hot casserole with hot Salsa de Tomatillo on the side.

    10 min

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